Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption

Mutations in the DJ-1 gene have been shown to cause a rare autosomal-recessive genetic form of Parkinson’s disease (PD). The function of DJ-1 and its role in PD development has been linked to multiple pathways, however its exact role in the development of PD has remained elusive. It is thought that...

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Bibliographic Details
Main Authors: Pamela Lopert, Manisha Patel
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000639