Oncolytic Efficacy of a Recombinant Vaccinia Virus Strain Expressing Bacterial Flagellin in Solid Tumor Models

Oncolytic Efficacy of a Recombinant Vaccinia Virus Strain Expressing Bacterial Flagellin in Solid Tumor Models

Oncolytic viral therapy is a promising novel approach to cancer treatment. Oncolytic viruses cause tumor regression through direct cytolysis on the one hand and recruiting and activating immune cells on the other. In this study, to enhance the antitumor efficacy of the thymidine kinase-deficient vac...

Full description

Bibliographic Details
Main Authors: Yasmin Shakiba, Pavel O. Vorobyev, Victor A. Naumenko, Dmitry V. Kochetkov, Ksenia V. Zajtseva, Marat P. Valikhov, Gaukhar M. Yusubalieva, Yana D. Gumennaya, Egor A. Emelyanov, Alevtina S. Semkina, Vladimir P. Baklaushev, Peter M. Chumakov, Anastasia V. Lipatova
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Viruses
Subjects:
vaccinia virus
LIVP
flagellin
cytokine analysis
virotherapy
IVIS
Online Access:https://www.mdpi.com/1999-4915/15/4/828

Internet

https://www.mdpi.com/1999-4915/15/4/828

Similar Items