Temperature-Dependent Ordering of the Methyl Group in the Crystal Structure of 5-(2-Chlorophenyl)-7-ethyl-1H-thieno [2,3-E][1,4]diazepin-2(3H)-one

Temperature-Dependent Ordering of the Methyl Group in the Crystal Structure of 5-(2-Chlorophenyl)-7-ethyl-1H-thieno [2,3-E][1,4]diazepin-2(3H)-one

5-(2-Chlorophenyl)-7-ethyl-1H-thieno[2,3-e][1,4]diazepin-2(3H)-one, a close analogue of clotiazepam (full agonist at GABA receptor), crystallizes in monoclinic P21/c space group with a = 15.6941(6) Å, b = 10.7909(4) Å, c = 8.6586(3) Å, and β = 102.184(4)° (at 125 K). Seven-Membered diazepine ring ha...

Full description

Bibliographic Details
Main Authors: Hemmige S. Yathirajan, Alaloor S. Dayananda, Maciej Kubicki, Grzegorz Dutkiewicz, Andagar R. Ramesha
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Crystals
Subjects:
diazepines
hydrogen bonding
disorder
structural change
Online Access:http://www.mdpi.com/2073-4352/2/3/1347

Internet

http://www.mdpi.com/2073-4352/2/3/1347

Similar Items