Encapsulation of β-NGF in injectable microrods for localized delivery accelerates endochondral fracture repair

Encapsulation of β-NGF in injectable microrods for localized delivery accelerates endochondral fracture repair

Introduction: Currently, there are no non-surgical FDA-approved biological approaches to accelerate fracture repair. Injectable therapies designed to stimulate bone healing represent an exciting alternative to surgically implanted biologics, however, the translation of effective osteoinductive thera...

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Bibliographic Details
Main Authors: Kevin O. Rivera, Darnell L. Cuylear, Victoria R. Duke, Kelsey M. O’Hara, Justin X. Zhong, Nafisa A. Elghazali, Joel A. Finbloom, Bhushan N. Kharbikar, Alex N. Kryger, Theodore Miclau, Ralph S. Marcucio, Chelsea S. Bahney, Tejal A. Desai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
fracture repair
endochondral ossification
beta-nerve growth factor
drug delivery
sustained release
poly (ethylene) glycol dimethacrylate
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1190371/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1190371/full

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