CMV reactivation initiates long-term expansion and differentiation of the NK cell repertoire

CMV reactivation initiates long-term expansion and differentiation of the NK cell repertoire

IntroductionNK cells play an important role in suppression of viral replication and are critical for effective control of persistent infections such as herpesviruses. Cytomegalovirus infection is associated with expansion of ‘adaptive-memory’ NK cells with a characteristic CD56dimCD16bright NKG2C+ p...

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Bibliographic Details
Main Authors: Norfarazieda Hassan, Suzy Eldershaw, Christine Stephens, Francesca Kinsella, Charles Craddock, Ram Malladi, Jianmin Zuo, Paul Moss
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
adaptive NK cells
NKG2C+
CMV reactivation
human cytomegalovirus
allogeneic HSCT
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.935949/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.935949/full

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