Dependence on Mincle and Dectin-2 Varies With Multiple Candida Species During Systemic Infection

Dependence on Mincle and Dectin-2 Varies With Multiple Candida Species During Systemic Infection

More than 95% of invasive Candida infections are caused by four Candida spp. (C. albicans, C. glabrata, C. tropicalis, C. parapsilosis). C-type lectin-like receptors (CLRs), such as Dectin-1, Dectin-2, and Mincle mediate immune responses to C. albicans. Dectin-1 promotes clearance of C. albicans, C....

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Bibliographic Details
Main Authors: Aiysha Thompson, Diogo M. da Fonseca, Louise Walker, James S. Griffiths, Philip R. Taylor, Neil A. R. Gow, Selinda J. Orr
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Microbiology
Subjects:
Mincle
Dectin-2
Candida
CLR
fungal
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.633229/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.633229/full

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