PTEN-regulated alternative splicing of FoxM1 affects tumor cell migration

Objective·To study the effect of phosphatase and tensin homolog on chromosome 10 (PTEN) on alternative splicing of forkhead box M1 (FoxM1), and its impact on tumor cell migration.Methods·PTEN was knocked down by short hairpin RNA (shRNA) in human embryonic kidney 293T cells, human...

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Bibliographic Details
Main Authors: WANG Xiaoling, GE Mengkai, SHEN Shaoming
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2023-11-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:
Online Access: https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-11-1339.shtml