Oocyte-specific disruption of adrenomedullin 2 gene enhances ovarian follicle growth after superovulation

BackgroundAdrenomedullin 2 (ADM2), adrenomedullin (ADM), and calcitonin gene-related peptides (α- and β-CGRPs) signal through heterodimeric calcitonin receptor-like receptor/receptor activity-modifying protein 1, 2 and 3 (CLR/RAMP1, 2 and 3) complexes. These peptides are important regulators of neur...

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Bibliographic Details
Main Authors: Chia Lin Chang, Wei-Che Lo, Ta-Hsien Lee, Jia-Yi Sung, Yen Ju Sung
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1047498/full