Novel Set of Diarylmethanes to Target Colorectal Cancer: Synthesis, <i>In Vitro</i> and <i>In Silico</i> Studies

Novel Set of Diarylmethanes to Target Colorectal Cancer: Synthesis, <i>In Vitro</i> and <i>In Silico</i> Studies

Distinctive structural, chemical, and physical properties make the diarylmethane scaffold an essential constituent of many active biomolecules nowadays used in pharmaceutical, agrochemical, and material sciences. In this work, 33 novel diarylmethane molecules aiming to target colorectal cancer were...

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Bibliographic Details
Main Authors: Ameni Hadj Mohamed, Aline Pinon, Nathalie Lagarde, Elizabeth Goya Jorge, Hadley Mouhsine, Moncef Msaddek, Bertrand Liagre, Maité Sylla-Iyarreta Veitía
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
diarylmethane
colorectal cancer
antiproliferative activity
apoptosis
molecular docking
ADME profile
Online Access:https://www.mdpi.com/2218-273X/13/1/54

Internet

https://www.mdpi.com/2218-273X/13/1/54

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