Purification, Characterization and in vitro Evaluation of Polymyxin A From Paenibacillus dendritiformis: An Underexplored Member of the Polymyxin Family

Purification, Characterization and in vitro Evaluation of Polymyxin A From Paenibacillus dendritiformis: An Underexplored Member of the Polymyxin Family

Nosocomial infections caused by antibiotic-resistant Gram-negative pathogens are of grave concern today. Polymyxins are considered as the last resorts of therapy to treat these multi-drug resistant (MDR) bacteria. But their associated nephrotoxicity and neurotoxicity calls for the development of saf...

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Bibliographic Details
Main Authors: Manoj Jangra, Harmandeep Kaur Randhawa, Manpreet Kaur, Anugya Srivastava, Navdezda Maurya, Prashant P. Patil, Pallavi Jaswal, Ashish Arora, Prabhu B. Patil, Manoj Raje, Hemraj Nandanwar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Microbiology
Subjects:
polymyxin A
gram-negative infections
Paenibacillus dendritiformis
antibiotic-resistance
antimicrobial agent
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02864/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02864/full

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