Autoreactive T Cells in Human Smokers Is Predictive of Clinical Outcome

Cross-sectional studies have suggested a role for activation of adaptive immunity in smokers with emphysema, but the clinical application of these findings has not been explored. Here we examined the utility of detecting autoreactive T cells as a screening tool for emphysema in an at-risk populatio...

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Main Authors: Chuang eXu, Sean eHesselbacher, Chu-Lin eTsai, Ming eShan, Margaret eSpitz, Michael eScheurer, Luz eRoberts, Sarah ePerusich, Nazanin eZarinkamar, Harvey eCoxson, Natasha eKrowchuk, David B Corry, Farrah eKheradmand
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00267/full