Peripheral Blood Microbiome Analysis via Noninvasive Prenatal Testing Reveals the Complexity of Circulating Microbial Cell-Free DNA

Peripheral Blood Microbiome Analysis via Noninvasive Prenatal Testing Reveals the Complexity of Circulating Microbial Cell-Free DNA

ABSTRACT While circulating cell-free DNA (cfDNA) is becoming a powerful marker for noninvasive identification of infectious pathogens in liquid biopsy specimens, a microbial cfDNA baseline in healthy individuals is urgently needed for the proper interpretation of microbial cfDNA sequencing results i...

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Bibliographic Details
Main Authors: Xunliang Tong, Xiaowei Yu, Yang Du, Fei Su, Ye Liu, Hexin Li, Yunshan Liu, Kai Mu, Qingsong Liu, Hui Li, Jiansheng Zhu, Hongtao Xu, Fei Xiao, Yanming Li
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
NIPT
microbiome
cfDNA
population-based analysis
noninvasive prenatal testing
cell-free circulating DNA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00414-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00414-22

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