hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells.

Cre-recombinase mediated conditional deletion of Lox-P site flanked ("floxed") genes is widely used for functional gene annotation in mice. Many different Cre-transgenic mouse lines have been developed for cell-type specific gene disruption. But often, the precise tissue-patterns of Cre ac...

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Detalles Bibliográficos
Main Authors: Sabine Siegemund, Jovan Shepherd, Changchun Xiao, Karsten Sauer
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC4401753?pdf=render