hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells.
Cre-recombinase mediated conditional deletion of Lox-P site flanked ("floxed") genes is widely used for functional gene annotation in mice. Many different Cre-transgenic mouse lines have been developed for cell-type specific gene disruption. But often, the precise tissue-patterns of Cre ac...
Main Authors: | , , , |
---|---|
Formato: | Artigo |
Idioma: | English |
Publicado: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Acceso en liña: | http://europepmc.org/articles/PMC4401753?pdf=render |