Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome

Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome

<p>Abstract</p> <p>Background</p> <p>The t(6;8) translocation found in rare and agressive myeloproliferative disorders results in a chimeric gene encoding the FOP-FGFR1 fusion protein. This protein comprises the N-terminal region of the centrosomal protein FOP and the t...

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Bibliographic Details
Main Authors: Tassin Anne-Marie, Chevrier Véronique, Lelièvre Hélène, Birnbaum Daniel
Format: Article
Language:English
Published: BMC 2008-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/30

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http://www.molecular-cancer.com/content/7/1/30

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