The interplay between prior selection, mild intermittent exposure, and acute severe exposure in phenotypic and transcriptional response to hypoxia

Abstract Hypoxia has profound and diverse effects on aerobic organisms, disrupting oxidative phosphorylation and activating several protective pathways. Predictions have been made that exposure to mild intermittent hypoxia may be protective against more severe exposure and may extend lifespan. Here...

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Bibliographic Details
Main Authors: Millicent N. Ekwudo, Morad C. Malek, Cora E. Anderson, Lev Y. Yampolsky
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Ecology and Evolution
Subjects:
Online Access:https://doi.org/10.1002/ece3.9319