Application of Drug Testing Platforms in Circulating Tumor Cells and Validation of a Patient-Derived Xenograft Mouse Model in Patient with Primary Intracranial Ependymomas with Extraneural Metastases

Application of Drug Testing Platforms in Circulating Tumor Cells and Validation of a Patient-Derived Xenograft Mouse Model in Patient with Primary Intracranial Ependymomas with Extraneural Metastases

Primary intracranial ependymoma is a challenging tumor to treat despite the availability of multidisciplinary therapeutic modalities, including surgical resection, radiotherapy, and adjuvant chemotherapy. After the completion of initial treatment, when resistant tumor cells recur, salvage therapy ne...

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Bibliographic Details
Main Authors: Muh-Lii Liang, Ting-Chi Yeh, Man-Hsu Huang, Pao-Shu Wu, Shih-Pei Wu, Chun-Chao Huang, Tsung-Yu Yen, Wei-Hsin Ting, Jen-Yin Hou, Jia-Yun Huang, Yi-Huei Ding, Jia-Huei Zheng, Hsi-Che Liu, Che-Sheng Ho, Shiu-Jau Chen, Tsung-Han Hsieh
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Diagnostics
Subjects:
ependymoma
extraneural metastasis
circulating tumor cells
patient-derived xenograft
drug screening
Online Access:https://www.mdpi.com/2075-4418/13/7/1232

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https://www.mdpi.com/2075-4418/13/7/1232

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