Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3

Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3

Summary: Hearing depends on precise synaptic transmission between cochlear inner hair cells and spiral ganglion neurons through afferent ribbon synapses.Neuroligins (Nlgns) facilitate synapse maturation in the brain, but they have gone unstudied in the cochlea. We report Nlgn3 and Nlgn1 knockout (KO...

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Bibliographic Details
Main Authors: Miguel A. Ramirez, Yuzuru Ninoyu, Cayla Miller, Leonardo R. Andrade, Seby Edassery, Ewa Bomba-Warczak, Briana Ortega, Uri Manor, Mark A. Rutherford, Rick A. Friedman, Jeffrey N. Savas
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
genomics
neuroscience
cellular neuroscience
sensory neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010756

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http://www.sciencedirect.com/science/article/pii/S2589004222010756

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