Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia

Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia

Abstract Background Acute lymphoblastic leukemia (ALL) is an aggressive hematopoietic malignancy that is most commonly observed in children. Alantolactone (ALT) has been reported to exhibit anti-tumor activity in different types of cancer. The aim of the present study was to investigate the anti-tum...

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Bibliographic Details
Main Authors: Ce Shi, Wenjia Lan, Zhenkun Wang, Dongguang Yang, Jia Wei, Zhiyu Liu, Yueqiu Teng, Mengmeng Gu, Tian Yuan, Fenglin Cao, Jin Zhou, Yang Li
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cancer Cell International
Subjects:
Alantolactone
Acute lymphoblastic leukemia
Adaptor related protein complex 2 subunit mu 1
Autophagy
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12935-020-01537-9

Internet

http://link.springer.com/article/10.1186/s12935-020-01537-9

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