Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia

Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia

Abstract Background Acute lymphoblastic leukemia (ALL) is an aggressive hematopoietic malignancy that is most commonly observed in children. Alantolactone (ALT) has been reported to exhibit anti-tumor activity in different types of cancer. The aim of the present study was to investigate the anti-tum...

Descrición completa

Detalles Bibliográficos
Main Authors: Ce Shi, Wenjia Lan, Zhenkun Wang, Dongguang Yang, Jia Wei, Zhiyu Liu, Yueqiu Teng, Mengmeng Gu, Tian Yuan, Fenglin Cao, Jin Zhou, Yang Li
Formato: Artigo
Idioma:English
Publicado: BMC 2020-09-01
Series:Cancer Cell International
Subjects:
Alantolactone
Acute lymphoblastic leukemia
Adaptor related protein complex 2 subunit mu 1
Autophagy
Apoptosis
Acceso en liña:http://link.springer.com/article/10.1186/s12935-020-01537-9

Internet

http://link.springer.com/article/10.1186/s12935-020-01537-9

Títulos similares