Bayesian parameter estimation for automatic annotation of gene functions using observational data and phylogenetic trees.

Gene function annotation is important for a variety of downstream analyses of genetic data. But experimental characterization of function remains costly and slow, making computational prediction an important endeavor. Phylogenetic approaches to prediction have been developed, but implementation of a...

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Bibliographic Details
Main Authors: George G Vega Yon, Duncan C Thomas, John Morrison, Huaiyu Mi, Paul D Thomas, Paul Marjoram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007948