A simplified two-marker immunohistochemistry strategy for Lynch syndrome screening in endometrial cancer patients

Objective To examine the efficacy of MSH6 and PMS2 immunohistochemistry (IHC) as a screening method for Lynch syndrome in endometrial cancer patients. Methods Through multidisciplinary discussions, an institutional MSH6 and PMS2 IHC-initiated cascade test (MSH6, PMS2 IHC→microsatellite instability [...

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Bibliographic Details
Main Authors: Ala Aiob, Yeo Rae Kim, Kidong Kim, Hyojin Kim, Yong Beom Kim, Duck Woo Kim, Jae Hong No, Soo Hyun Seo, Dong Hoon Suh, Kyoung Un Park
Format: Article
Language:English
Published: Korean Society of Obstetrics and Gynecology 2023-11-01
Series:Obstetrics & Gynecology Science
Subjects:
Online Access:http://www.ogscience.org/upload/pdf/ogs-23124.pdf