Development and Validation of a 9-Gene Prognostic Signature in Patients With Multiple Myeloma

Development and Validation of a 9-Gene Prognostic Signature in Patients With Multiple Myeloma

Background: Multiple myeloma (MM) is one of the most common types of hematological malignance, and the prognosis of MM patients remains poor.Objective: To identify and validate a genetic prognostic signature in patients with MM.Methods: Co-expression network was constructed to identify hub genes rel...

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Bibliographic Details
Main Authors: Xiao-Ping Liu, Xiao-Hong Yin, Xiang-Yu Meng, Xin-Hui Yan, Fan Wang, Li He
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Subjects:
multiple myeloma
weighted co-expression network analysis
prognostic signature
LASSO Cox proportional hazards regression model
survival
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00615/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00615/full

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