Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy.

Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy.

Chronic Chagas cardiomyopathy (CCC) is one of the leading causes of morbidity and mortality due to cardiovascular disorders in endemic areas of Chagas disease (CD), a neglected tropical illness caused by the protozoan parasite Trypanosoma cruzi. CCC is characterized by parasite persistence and infla...

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Bibliographic Details
Main Authors: Priscila Silva Grijó Farani, Beatriz Iandra da Silva Ferreira, Khodeza Begum, Glaucia Vilar-Pereira, Isabela Resende Pereira, Edith A Fernández-Figueroa, Roberto Alejandro Cardenas-Ovando, Igor C Almeida, Sourav Roy, Joseli Lannes-Vieira, Otacilio Cruz Moreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011223

Internet

https://doi.org/10.1371/journal.pntd.0011223

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