Insight into the Natural History of Pathogenic Variant c.919-2A>G in the <i>SLC26A4</i> Gene Involved in Hearing Loss: The Evidence for Its Common Origin in Southern Siberia (Russia)

Insight into the Natural History of Pathogenic Variant c.919-2A>G in the <i>SLC26A4</i> Gene Involved in Hearing Loss: The Evidence for Its Common Origin in Southern Siberia (Russia)

Pathogenic variants in the <i>SLC26A4</i> gene leading to nonsyndromic recessive deafness (DFNB4), or Pendred syndrome, are some of the most common causes of hearing loss worldwide. Earlier, we found a high proportion of <i>SLC26A4</i>-related hearing loss with prevailing pat...

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Bibliographic Details
Main Authors: Valeriia Yu. Danilchenko, Marina V. Zytsar, Ekaterina A. Maslova, Konstantin E. Orishchenko, Olga L. Posukh
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
hearing loss
<i>SLC26A4</i>
c.919-2A>G
founder effect
STR and SNP haplotypes
Tuvinians
Online Access:https://www.mdpi.com/2073-4425/14/4/928

Internet

https://www.mdpi.com/2073-4425/14/4/928

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