High-efficient production of mushroom polyketide compounds in a platform host Aspergillus oryzae

Abstract Background Orsellinic acid (2,4-dihydroxy-6-methylbenzoic acid, OA) and its structural analog o-Orsellinaldehyde, have become widely used intermediates in clinical drugs synthesis. Although the research on the biosynthesis of such compounds has made significant progress, due to the lack of...

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Bibliographic Details
Main Authors: Haiyan Han, Chunyan Yu, Jianzhao Qi, Pengchao Wang, Peipei Zhao, Wenbing Gong, Chunliang Xie, Xuekui Xia, Chengwei Liu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-023-02071-9