P2Y2 receptor mediates dying cell removal via inflammatory activated microglia

P2Y2 receptor mediates dying cell removal via inflammatory activated microglia

Microglial removal of dying cells plays a beneficial role in maintaining homeostasis in the CNS, whereas under some pathological conditions, inflammatory microglia can cause excessive clearance, leading to neuronal death. However, the mechanisms underlying dying cell removal by inflammatory microgli...

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Bibliographic Details
Main Authors: Izumi Hide, Hiroko Shiraki, Akihiro Masuda, Takuya Maeda, Mayuka Kumagai, Nao Kunishige, Yuhki Yanase, Kana Harada, Shigeru Tanaka, Norio Sakai
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Microglia
Inflammation
Dying cell removal
Lipopolysaccharide
P2Y2 receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861323000385

Internet

http://www.sciencedirect.com/science/article/pii/S1347861323000385

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