Anti-CXCR4 Single-Chain Variable Fragment Antibodies Have Anti-Tumor Activity

Monoclonal antibodies (mAbs) are large and have limitations as cancer therapeutics. Human single-chain variable fragment (scFv) is a small antibody as a good alternative. It can easily enter cancer tissues, has no immunogenicity and can be produced in bacteria to decrease the cost. The chemokine rec...

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Bibliographic Details
Main Authors: Guang-Quan Liang, Jing Liu, Xiao-Xin Zhou, Ze-Xiong Lin, Tao Chen, Guo Chen, Henry Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.571194/full