Starvation-Sensitized and Oxygenation-Promoted Tumor Sonodynamic Therapy by a Cascade Enzymatic Approach

The therapeutic outcomes of noninvasive sonodynamic therapy (SDT) are always compromised by tumor hypoxia, as well as inherent protective mechanisms of tumor. Herein, we report a simple cascade enzymatic approach of the concurrent glucose depletion and intratumoral oxygenation for starvation-sensiti...

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Bibliographic Details
Main Authors: Wencheng Wu, Yinying Pu, Han Lin, Heliang Yao, Jianlin Shi
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021-01-01
Series:Research
Online Access:http://dx.doi.org/10.34133/2021/9769867