A Comprehensive Review of the Genomics of Multiple Myeloma: Evolutionary Trajectories, Gene Expression Profiling, and Emerging Therapeutics

A Comprehensive Review of the Genomics of Multiple Myeloma: Evolutionary Trajectories, Gene Expression Profiling, and Emerging Therapeutics

Multiple myeloma (MM) is a blood cancer characterized by the accumulation of malignant monoclonal plasma cells in the bone marrow. It develops through a series of premalignant plasma cell dyscrasia stages, most notable of which is the Monoclonal Gammopathy of Undetermined Significance (MGUS). Signif...

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Bibliographic Details
Main Authors: Hassan Awada, Bicky Thapa, Hussein Awada, Jing Dong, Carmelo Gurnari, Parameswaran Hari, Binod Dhakal
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
multiple myeloma
plasma cell dyscrasia
genomics
risk stratification
prognosis
Online Access:https://www.mdpi.com/2073-4409/10/8/1961

Internet

https://www.mdpi.com/2073-4409/10/8/1961

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