Proteomic profiling of single extracellular vesicles reveals colocalization of SARS-CoV-2 with a CD81/integrin-rich EV subpopulation in sputum from COVID-19 severe patients

BackgroundThe global outbreak of COVID-19, and the limited availability of clinical treatments, forced researchers around the world to search for the pathogenesis and potential treatments. Understanding the pathogenesis of SARS-CoV-2 is crucial to respond better to the current coronavirus disease 20...

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Main Authors: Ruiting Sun, Yanling Cai, Yumin Zhou, Ge Bai, Airu Zhu, Panyue Kong, Jing Sun, Yimin Li, Yuefei Liu, Wenting Liao, Jiye Liu, Nan Cui, Jinsheng Xiang, Bing Li, Jincun Zhao, Di Wu, Pixin Ran
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1052141/full