Furin cleavage sites naturally occur in coronaviruses

The spike protein is a focused target of COVID-19, a pandemic caused by SARS-CoV-2. A 12-nt insertion at S1/S2 in the spike coding sequence yields a furin cleavage site, which raised controversy views on origin of the virus. Here we analyzed the phylogenetic relationships of coronavirus spike protei...

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Bibliographic Details
Main Authors: Yiran Wu, Suwen Zhao
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120304165