Overexpression of Global Regulator SCrp Leads to the Discovery of New Angucyclines in <i>Streptomyces</i> sp. XS-16

Overexpression of Global Regulator SCrp Leads to the Discovery of New Angucyclines in <i>Streptomyces</i> sp. XS-16

Six angucyclines including three unreported compounds (<b>1</b>–<b>3</b>) were isolated from <i>Streptomyces</i> sp. XS-16 by overexpressing the native global regulator of SCrp (cyclic AMP receptor). The structures were characterized based on nuclear magnetic reso...

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Bibliographic Details
Main Authors: Xiao Xu, Falei Zhang, Luning Zhou, Yimin Chang, Qian Che, Tianjiao Zhu, Dehai Li, Guojian Zhang
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Marine Drugs
Subjects:
overexpression
global regulator
SCrp
angucyclines
<i>Streptomyces</i> sp.
Online Access:https://www.mdpi.com/1660-3397/21/4/240

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https://www.mdpi.com/1660-3397/21/4/240

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