Exploration of mechanisms of α-linolenic acid in reducing the growth of oestrogen receptor positive breast cancer cells (MCF-7)
The n-3 fatty acid α-linolenic acid (ALA) inhibits oestrogen receptor (ER) positive MCF-7 cell growth in vitro and in vivo. Our objective was to explore potential mechanisms. MCF-7 cells were treated with 100 µM ALA and 1 nM oestradiol (E2) then analysed for fatty acid profile, mRNA and protein biom...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-06-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464616301128 |