Allele frequencies of dopamine D4 receptor gene (DRD4) and Catechol-O-methyltransferase (COMT) Val158Met polymorphism are associated with methylphenidate response in adolescents with attention deficit/hyperactivity disorder: a case control preliminary study

Allele frequencies of dopamine D4 receptor gene (DRD4) and Catechol-O-methyltransferase (COMT) Val158Met polymorphism are associated with methylphenidate response in adolescents with attention deficit/hyperactivity disorder: a case control preliminary study

OBJECTIVES: In this study, it was aimed to analyse the relationship between clinical improvement in adolescents with attention deficit/hyperactivity disorder (ADHD) and the presence of allele frequencies of dopamine D4 receptor (DRD4), and Val158Met polymorphism of catechol-O-methyltransferase (COMT...

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Bibliographic Details
Main Authors: Aynur Pekcanlar Akay, Çiğdem Eresen Yazıcıoğlu, Sevay Alşen Güney, Handan Özek Erkuran, Sefa Kızıldağ, Burak Baykara, Gonca Özyurt, Şebnem Yıldırımcan Kadıçeşme, Süha Miral, Neslihan İnal Emiroğlu
Format: Article
Language:English
Published: AVES 2018-04-01
Series:Psychiatry and Clinical Psychopharmacology
Subjects:
Attention deficit/hyperactivity disorder
adolescents
catechol-O-methyltransferase gene (COMT)
dopamine D4 receptor gene (DRD4)
methylphenidate
clinical global impression (CGI)
Online Access:http://dx.doi.org/10.1080/24750573.2017.1418134

Internet

http://dx.doi.org/10.1080/24750573.2017.1418134

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