The aminoglycoside antibiotic gentamicin is able to alter metabolic activity and morphology of MDCK-C11 cells: a cell model of intercalated cells

It is well known that the aminoglycoside antibiotic gentamicin is capable of causing damage to kidney cells. Given the known involvement of Ca2+ in the nephrotoxic action of gentamicin, the purpose of this study was to establish a relationship between the concentration of intracellular Ca2+ ([Ca2+]i...

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Bibliographic Details
Main Authors: A.G.G. Coutinho, S.M.P. Biscaia, R. Fernandez, A.L. Tararthuch
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000610&lng=en&tlng=en