Human Melanocyte-Derived Spheroids: A Precise Test System for Drug Screening and a Multicellular Unit for Tissue Engineering

Human Melanocyte-Derived Spheroids: A Precise Test System for Drug Screening and a Multicellular Unit for Tissue Engineering

Pigmentation is the result of melanin synthesis, which takes place in melanocytes, and its further distribution. A dysregulation in melanocytes' functionality can result in the loss of pigmentation, the appearance of pigment spots and melanoma development. Tissue engineering and the screening o...

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Bibliographic Details
Main Authors: Irina M. Zurina, Anastasiya A. Gorkun, Ekaterina V. Dzhussoeva, Tamara D. Kolokoltsova, Dmitriy D. Markov, Nastasia V. Kosheleva, Sergey G. Morozov, Irina N. Saburina
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
melanocyte
melanogenesis
spheroid
3D culture
drug screening
tissue engineering
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00540/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00540/full

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