Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects.

Targeted nanoparticle delivery is a promising strategy for increasing efficacy and limiting side effects of therapeutics. When designing a targeted liposomal formulation, the in vivo biodistribution of the particles must be characterized to determine the value of the targeting approach. Peroxisome p...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Dustin K Bauknight, Victoria Osinski, Siva Sai Krishna Dasa, Anh T Nguyen, Melissa A Marshall, Julia Hartman, Matthew Harms, Gavin O'Mahony, Jeremie Boucher, Alexander L Klibanov, Coleen A McNamara, Kimberly A Kelly
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Public Library of Science (PLoS) 2019-01-01
Sarja:PLoS ONE
Linkit:https://doi.org/10.1371/journal.pone.0224917