The effect of age and sex on the expression of GABA signaling components in the human hippocampus and entorhinal cortex

Abstract Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the nervous system. The GABA signaling system in the brain is comprised of GABA synthesizing enzymes, transporters, GABAA and GABAB receptors (GABAAR and GABABR). Alterations in the expression of these signaling co...

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Bibliographic Details
Main Authors: Jayarjun Ethiraj, Thulani Hansika Palpagama, Clinton Turner, Bert van der Werf, Henry John Waldvogel, Richard Lewis Maxwell Faull, Andrea Kwakowsky
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00792-8