Axl regulated survival/proliferation network and its therapeutic intervention in mouse models of glomerulonephritis

Abstract Background Lupus nephritis (LN) is the most common and serious complication of systemic lupus erythematosus (SLE). LN pathogenesis is not fully understood. Axl receptor tyrosine kinase is upregulated and contributes to the pathogenic progress in LN. We have reported that Axl disruption atte...

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Bibliographic Details
Main Authors: Yuxuan Zhen, Yan Ren, Mario Medvedovic, David E. Adams, Diping Wang, Wen-Hai Shao
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-022-02965-w