Involvement of the carboxyl-terminal region of the yeast peroxisomal half ABC transporter Pxa2p in its interaction with Pxa1p and in transporter function.

The peroxisome is a single membrane-bound organelle in eukaryotic cells involved in lipid metabolism, including β-oxidation of fatty acids. The human genetic disorder X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene (encoding ALDP, a peroxisomal half ATP-binding cassett...

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Main Authors: Cheng-Yi Chuang, Ling-Yun Chen, Ru-Huei Fu, Shih-Ming Chen, Ming-Hua Ho, Jie-Mau Huang, Chia-Chi Hsu, Chien-Cheng Wang, Meng-Shian Chen, Rong-Tzong Tsai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4132065?pdf=render