Cannabinoid Biosynthesis Using Noncanonical Cannabinoid Synthases

Cannabinoid Biosynthesis Using Noncanonical Cannabinoid Synthases

We report enzymes from the berberine bridge enzyme (BBE) superfamily that catalyze the oxidative cyclization of the monoterpene moiety in cannabigerolic acid (CBGA) to form cannabielsoin (CBE). The enzymes are from a variety of organisms and are previously uncharacterized. Out of 232 homologues chos...

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Bibliographic Details
Main Authors: Maybelle Kho Go, Tingting Zhu, Kevin Jie Han Lim, Yossa Dwi Hartono, Bo Xue, Hao Fan, Wen Shan Yew
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
cannabinoid biosynthesis
cannabinoid synthase
berberine bridge enzyme
cannabielsoin
cannabigerolic acid
<i>Pichia pastoris</i>
Online Access:https://www.mdpi.com/1422-0067/24/2/1259

Internet

https://www.mdpi.com/1422-0067/24/2/1259

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