Deficiency of Urokinase Plasminogen Activator May Impair β Cells Regeneration and Insulin Secretion in Type 2 Diabetes Mellitus

Deficiency of Urokinase Plasminogen Activator May Impair β Cells Regeneration and Insulin Secretion in Type 2 Diabetes Mellitus

<b>: </b>Background: The relationship between urokinase-type plasminogen activator (uPA) and the development of type 2 diabetes mellitus (T2DM) was investigated in the study by using mice and cell models, as well as patients with T2DM. Methods: In mice models, wild-type and uPA knockout...

Полное описание

Библиографические подробности
Главные авторы:	Chung-Ze Wu, Shih-Hsiang Ou, Li-Chien Chang, Yuh-Feng Lin, Dee Pei, Jin-Shuen Chen
Формат:	Статья
Язык:	English
Опубликовано:	MDPI AG 2019-11-01
Серии:	Molecules
Предметы:	urokinase plasminogen activator type 2 diabetes mellitus insulin secretion β cell regeneration
Online-ссылка:	https://www.mdpi.com/1420-3049/24/23/4208

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