Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection.

During human and murine cytomegalovirus (MCMV) infection an exceptionally large virus-specific CD8 T cell pool is maintained in the periphery lifelong. This anomalous response is only seen for specific subsets of MCMV-specific CD8 T cells which are referred to as 'inflationary T cells'. Ho...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Nicole Torti, Senta M Walton, Thomas Brocker, Thomas Rülicke, Annette Oxenius
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2011-10-01
Schriftenreihe:PLoS Pathogens
Online Zugang:http://europepmc.org/articles/PMC3203160?pdf=render