Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast

Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast

Actin cables affect lifespan by supporting movement and inheritance of fitter mitochondria to daughter cells in yeast. Here the authors show that branched-chain amino acid (BCAA) levels affect actin cable stability and a role for YKL075C/AAN1 in control of BCAA metabolism and actin cable stability a...

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Bibliographic Details
Main Authors: Cierra N. Sing, Enrique J. Garcia, Thomas G. Lipkin, Thomas M. Huckaba, Catherine A. Tsang, Arielle C. Coughlin, Emily J. Yang, Istvan R. Boldogh, Ryo Higuchi-Sanabria, Liza A. Pon
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30045-9

Internet

https://doi.org/10.1038/s41467-022-30045-9

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