Fenofibrate Administration Reduces Alcohol and Saccharin Intake in Rats: Possible Effects at Peripheral and Central Levels

Fenofibrate Administration Reduces Alcohol and Saccharin Intake in Rats: Possible Effects at Peripheral and Central Levels

We have previously shown that the administration of fenofibrate to high-drinker UChB rats markedly reduces voluntary ethanol intake. Fenofibrate is a peroxisome proliferator-activated receptor alpha (PPARα) agonist, which induces the proliferation of peroxisomes in the liver, leading to increases in...

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Bibliographic Details
Main Authors: Mario Rivera-Meza, Daniel Muñoz, Erik Jerez, María E. Quintanilla, Catalina Salinas-Luypaert, Katia Fernandez, Eduardo Karahanian
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
fibrates
catalase
alcoholism
treatment
peroxisome proliferator-activated receptor alpha
Online Access:http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00133/full

Internet

http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00133/full

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