Tanshinone IIA alleviates atherosclerosis in LDLR−/− mice by regulating efferocytosis of macrophages

Tanshinone IIA alleviates atherosclerosis in LDLR−/− mice by regulating efferocytosis of macrophages

Background: Tanshinone IIA (TIIA) is the major lipid-soluble active ingredient of the traditional Chinese medicine Salvia miltiorrhiza, which slows down atherosclerosis (AS). However, it remains unclear whether TIIA has the potential to enhance macrophage efferocytosis and thereby improve atheroscle...

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Bibliographic Details
Main Authors: Jiarou Wang, Yifan Zhang, Xiaoteng Feng, Min Du, Sijin Li, Xindi Chang, Ping Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
tanshinone IIA
efferocytosis
macrophage
lipid metabolism
atherosclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1233709/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1233709/full

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