TAZ facilitates breast tumor growth by promoting an immune‐suppressive tumor microenvironment

TAZ facilitates breast tumor growth by promoting an immune‐suppressive tumor microenvironment

The core Hippo pathway module consists of a tumour‐suppressive kinase cascade that inhibits the transcriptional coactivators Yes‐associated protein (YAP) and WW domain‐containing transcription regulator protein 1 (WWTR1; also known as TAZ). When the Hippo pathway is downregulated, as often occurs in...

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Bibliographic Details
Main Authors: Anat Gershoni, Ori Hassin, Nishanth Belugali Nataraj, Sivan Baruch, Adi Avioz‐Seligman, Anna Chiara Pirona, Liat Fellus‐Alyagor, Tomer Meir Salame, Saptaparna Mukherjee, Giuseppe Mallel, Yosef Yarden, Yael Aylon, Moshe Oren
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Molecular Oncology
Subjects:
breast cancer
Hippo pathway
TAZ
Tregs
Online Access:https://doi.org/10.1002/1878-0261.13525

Internet

https://doi.org/10.1002/1878-0261.13525

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