Single-cell RNA sequencing explores the evolution of the ecosystem from leukoplakia to head and neck squamous cell carcinoma

Single-cell RNA sequencing explores the evolution of the ecosystem from leukoplakia to head and neck squamous cell carcinoma

Abstract It has been found that progression from leukoplakia to head and neck squamous cell carcinoma (HNSCC) is a long-term process that may involve changes in the multicellular ecosystem. We acquired scRNA-seq samples information from gene expression omnibus and UCSC Xena database. The BEAM functi...

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Bibliographic Details
Main Authors: Haibin Wang, Zhenjie Guan, Lian Zheng
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Head and neck squamous cell carcinoma
Leukoplakia
Ecosystem evolution
Differentiation trajectory
Prognosis
Online Access:https://doi.org/10.1038/s41598-024-58978-9

Internet

https://doi.org/10.1038/s41598-024-58978-9

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