Lipid Membrane‐Based Antigen Presentation to B Cells Using a Fully Synthetic Ex Vivo Germinal Center Model

Lipid Membrane‐Based Antigen Presentation to B Cells Using a Fully Synthetic Ex Vivo Germinal Center Model

High‐affinity antigen‐specific B cells are generated within specialized structures, germinal centers (GCs), inside lymphoid organs. In GCs, follicular dendritic cells (FDCs) present antigens on their membrane surface to cognate B cells, inducing rapid proliferation and differentiation of the B cells...

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Bibliographic Details
Main Authors: Liana Kramer, Hannah W. Song, Kaiya Mitchell, Mythili Kartik, Ritika Jain, Victoria Lozano Escarra, Enrique Quiros, Harrison Fu, Ankur Singh, Krishnendu Roy
Format: Article
Language:English
Published: Wiley-VCH 2022-07-01
Series:Advanced NanoBiomed Research
Subjects:
antigen
B cell receptors
B cells
liposomes
vaccine
Online Access:https://doi.org/10.1002/anbr.202100137

Internet

https://doi.org/10.1002/anbr.202100137

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