Discrete Element Method Evaluation of Triboelectric Charging Due to Powder Handling in the Capsule of a DPI

Discrete Element Method Evaluation of Triboelectric Charging Due to Powder Handling in the Capsule of a DPI

The generation and accumulation of an electrostatic charge from handling pharmaceutical powders is a well-known phenomenon, given the insulating nature of most APIs (Active Pharmaceutical Ingredients) and excipients. In capsule-based DPIs (Dry Powder Inhalers), the formulation is stored in a gelatin...

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Detalles Bibliográficos
Autores principales: Francesca Orsola Alfano, Alberto Di Renzo, Francesco Paolo Di Maio
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2023-06-01
Colección:Pharmaceutics
Materias:
triboelectric charging
electrostatics
DPI
DEM
inhalation
carrier-based formulation
Acceso en línea:https://www.mdpi.com/1999-4923/15/6/1762

Internet

https://www.mdpi.com/1999-4923/15/6/1762

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